Re: TOJC: Re Oxymerc vs. acid cat.

Craig Fryhle (fryhle@u.washington.edu)
Mon, 2 Dec 1996 22:27:21 -0800 (PST)

A point of correction here. Oxymercuration does not lead to
anti-Markovnikov regiochemistry. Oxymercuration leads to Markovnikov
addition.

CBF

On Mon, 2 Dec 1996 partaina@PLU.edu wrote:

>
> If i am not mistaken, oxymercuration etc. also provides a method for anti
> Markovnikov synthesis.
> Neil
>
> On Mon, 2 Dec 1996, Kari Fosser wrote:
>
> >
> > Casey,
> > The big difference between acid catalyzed hydration and
> > oxymercuration-demercuration is that rearrangements often occur in acid
> > catalyzed hydration while the mechanism for oxymercuration prevents that
> > from happening. Hope that helps.
> >
> > Kari
> >
> >
>
>

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