Re: tojc
heathbm@plu.edu
Thu, 12 Dec 1996 16:52:35 -0800 (PST)
I think that what was meant in the notes was that one molecule of Grignard
reagent will not make an ester go directly to an alcohol. Two molecules
of the Grignard reagent are needed because the ketone that is formed from
the attack by the Grignard reagent must react with another molecule of the
Grignard in order to get a tertiary alcohol. In the notes, I think that
it was saying that to directly go from an ester to an alcohol can not be
done with one molecule of the Grignard but it can be done with R"Li and
H3O+. I hope I have that right, the explanation about esters and Grignard
are on page 485.
On Thu, 12 Dec 1996 mcdowekm@plu.edu wrote:
>
>
> I have something in my notes about Grignard reagents not reacting
> with esters. Is this right? Can someone explain?
>
>