Re: TOJC GRINGARD yields

uhlerdd@plu.edu
Thu, 12 Dec 1996 22:22:29 -0800 (PST)

Stephanie and Shana,
I read the e-mail regarding the yields for Grignard reaction this
morning, I was wondering about the yields as well. I asked Dr. Fryhle
this afternoon in the study group. Dr. Fryhle said that the absorptivity
of CO2 for atmospheric H2O. The CO2 step greatly compromised the
anhydrous conditions needed for the Grignard reaction. He also mentioned
reagents that are commercially availible other than CO2 that do not
introduce H2O into the reaction conditions. Well, I guess that explains
the lower yields.
Dave

On Thu, 12 Dec 1996 mcgillsa@plu.edu wrote:

> Stephanie,
>
> Perhaps the actual Grignard reagent step has a high yield but not the step
> using the reagent that follows it?? It's just an idea... WE cannot
> calculate the yield of the reagent itself, since we just went on with the
> experiment, but perhaps that is what they meant?? ;)
> Shana M.
>
> On Thu, 12 Dec 1996 becksm@plu.edu wrote:
>
> >
> > In the book it says that Gringard reagents almost always have high yields
> > (85-95%) From talking to others in the class, most got below 10% yield in
> > the lab. Are we just to inexperienced in this type of reaction, or is
> > this one of those things you just can't explain. (That seemed to be the
> > answer from both professors who were in lab when I asked them any
> > questions about the experiment.)
> >
> > Stephanie
> >
> >
> >
>
>