Re: leaving groups

hiattzr@plu.edu
Tue, 18 Mar 1997 14:03:03 -0800 (PST)

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cas,
To answer this question, it helps to think that because a base can
stabilize a neg. charge, it is a weak base, rather than just trying to
memorize the fact that weak bases stabilize a neg. charge. A weak base is
able to stabilize its neg charge through
inductive effects of various electronegative groups, or the possibility of
resonance hybridization in the molecule (the base). This causes a
dispersion of the neg
charge in the molecule and the base is better able to hold (or happier to
have) the neg charge and so it is more stable, or a WEAKER BASE.

On Mon, 17 Mar 1997 shorescf@plu.edu wrote:

> On page 256 of Solomons it states that weak bases stabalize a negative
> charge most effectively. Why is this?
>
> thanks-
> cas
>
>

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